OGF-OGFr通路与肿瘤治疗研究进展(4)
OGF-OGFr通路广泛存在,对细胞存在着剂量依赖的、可逆的、受体介导、无细胞毒性的生长抑制作用,这无疑对肿瘤的生物治疗有重要意义。但还需要对更多不同组织学类型和分化程度的癌症进一步研究以积累更多的经验。OGF-OGFr通路与更多治疗方法的联合应用效果及如何应用尚不明确。由于OGFr的突变会影响此通路的功能,这也使它在治疗中的应用受到限制。随着相应研究的深入和技术手段的进步,关于此通路更多的研究进展会被不断发现,其局限性也将被逐渐克服,OGF-OGFr通路会在肿瘤治疗中发挥更大的作用。
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文章来源:《中国肿瘤生物治疗杂志》 网址: http://www.zgzlswzlzz.cn/qikandaodu/2020/1224/468.html
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